John Mayall & the Bluesbreakers are an English blues rock band led by singer, songwriter, and multi-instrumentalist John Mayall. While never producing a radio hit of their own, the band has been hugely influential as an incubator for British rock and blues musicians. Many of the best known bands to come out of Britain in the 1960s and 1970s had members that came through the Bluesbreakers at one time, forming the foundation of British blues music that is still played heavily on classic rock radio. Among those with a tenure in the Bluesbreakers are Eric Clapton and Jack Bruce (both later of Cream), Peter Green, Mick Fleetwood, and John McVie (the three of whom would form Fleetwood Mac), Mick Taylor (the Rolling Stones), Aynsley Dunbar (Frank Zappa and The Mothers of Invention), Jon Hiseman, Dick Heckstall-Smith and Tony Reeves (these three would form Colosseum (band)), and numerous others.

Mayall used the band name between 1963 and 1967, then dropped it for some fifteen years. In 1982 a 'Return of the Bluesbreakers' was announced, and the name was used until the band again dissolved in 2008. The name has become generic, without a clear distinction between recordings by Mayall alone and those by Mayall and his band.